Ex-Vivo Therapeutic Assessments on Patient Derived Organotypic Tumor Spheroids

• • • • • • • • Xsphera procures qualified patient tumor samples for the study from its clinical site network
              • Immune profiling is performed on each patient sample
              • Post-treatment assessments include: cytotoxicity, cytokine expression, and gene expression
              • The number of study arms can range from 2 to greater than 10 per patient sample
              • Murine tumors or human cancer cell lines can be studied instead of patient tumor tissue
                

Human Tumor Target Expression

• • • • • • • • Assess proprietary target expression levels on specified patient populations